📌 About AllerTrans – A Powerful Tool for Predicting the Allergenicity of Protein Sequences

🧬 Input Format – FASTA Sequences: This tool accepts protein sequences in FASTA format.

Please provide a single protein sequence at a time.

For faster predictions, you can enter just the protein sequence, without the FASTA header or any additional information.

🧾 Output Explanation – AllerTrans classifies your input sequence into one of the following categories:

🟢 Non-Allergen: The protein is unlikely to cause an allergic reaction and can be considered safe regarding allergenicity.

🔴 Potential Allergen: The protein has the potential to trigger an allergic response or exhibit cross-reactivity in some individuals.

🔎 Caution & Disclaimer:

Our model has demonstrated promising performance on the AlgPred 2.0 validation set, which includes a wide range of allergenic and non-allergenic sequences from diverse sources. AllerTrans is also capable of handling recombinant proteins, as supported by additional evaluation using a recombinant protein dataset from UniProt. However, we advise caution when using this tool on all constructs and modifications of recombinant proteins. The model's generalizability across various recombinant scenarios has yet to be fully explored.

🚨 Remember, AllerTrans is designed as a reliable screening tool. However, for clinical or regulatory decisions, always confirm the prediction results through experimental validation.